The 12th International Semantic Web Conference
and the 1st Australasian Semantic Web Conference
21-25 October 2013, Sydney, Australia

A Protein Annotation Framework Empowered with Semantic Reasoning

Jemma Wu, Edmond Breen, Xiaomin Song, Brett Cooke and Mark Molloy
This paper presents an association discovery framework for proteins based on semantic annotations from biomedical literatures. An automatic ontology-based annotation method is used to create a semantic protein annotation knowledge base. A semantic reasoning service enables realisation reasoning on original annotations to infer more accurate associations. A case study on protein-disease association discovery on a real-world colorectal cancer dataset is presented.
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